学术论文
1. Photon-by-Photon Fluorescence Lifetime Analysis of Within-Burst State Transitions of Single Proteins in Lipid Membranes, Hao Wang,# Hang Fu,# Ye Yuan, Chenguang Yang, Zhao Lin, Tongsheng Chen, Chunhua Xu, Shuxin Hu, Ming Li,* and Ying Lu*, J. Am. Chem. Soc. 2025, 147(32): 28552-28557
2. Protonation-Regulated Membrane-Insertion Dynamics of pH Low-Insertion Peptide: Metastable Molecular Conformations and Their Transitions, Jie Qiu#, Dongfei Ma#, Xin You, Qi Jia, Shuxin Hu, Cheng Xu, Binglong Cao, Kai Yang,* Weijing Han,* Ying Lu,* Bing Yuan,* and Ming Li, ACS Nano, 2025, 19(16): 15685-15697
3. Real-time analysis of nanoscale dynamics in membrane protein insertion via single-molecule imaging, Chenguang Yang, Dongfei Ma, Shuxin Hu, Ming Li, Ying Lu*, Biophysics Reports, 2024, 10(6):369-376
4. Single-molecule reconstruction of eukaryotic factor-dependent transcription termination, Ying Xiong#, Weijing Han#, Chunhua Xu#, Jing Shi#, Lisha Wang, Taoli Jin, Qi Jia, Ying Lu, Shuxin Hu, Shuo-Xing Dou, Wei Lin, Terence R. Strick*, Shuang Wang*, Ming Li, Nat. Commun., 2024, 15(1): 5113
5. Sodium Ion-Induced Structural Transition on the Surface of a DNA-Interacting Protein, Chunhua Xu#, Yue Lu#, Yichao Wu#, Shuaikang Yuan#, Jianbing Ma, Hang Fu, Hao Wang, Libang Wang, Hao Zhang, Xuan Yu, Wei Tao, Chang Liu, Shuxin Hu, Yi Peng, Wenfei Li*, Yunliang Li*, Ying Lu*, and Ming Li*, Adv. Sci., 2024, 11(42): e2401838
6. Single-molecule characterization of Sen1 translocation properties provides insights into eukaryotic factor-dependent transcription termination, Shuang Wang*, Zhong Han and Terence R. Strick*, Nucleic Acids Res., 2024, 52(6): 3249
7. Dissecting the mechanism of atlastin-mediated homotypic membrane fusion at the single-molecule level, Lijun Shi#, Chenguang Yang#, Mingyuan Zhang, Kangning Li, Keying Wang, Li Jiao, Ruming Liu, Yunyun Wang, Ming Li, Yong Wang*, Lu Ma*, Shuxin Hu*, Xin Bian*, Nat. Commun., 2024, 15(1): 2488
8. Self-limiting multimerization of alpha-synuclein on membrane and its implication in Parkinson's diseases, Dong- Fei Ma#, Shenqing Zhang#, Si- Yao Xu#, Zi Huang, Yuanxiao Tao, Feiyang Chen, Shengnan Zhang, Dan Li, Tongsheng Chen, Cong Liu*, Ming Li*, Ying Lu*, Sci. Adv., 2024, 10(41): eado4893
9. Four Parallel Pathways in T4 Ligase-Catalyzed Repair of Nicked DNA with Diverse Bending Angles, Na Li#, Jianbing Ma#, Hang Fu#, Zhiwei Yang#, Chunhua Xu, Haihong Li, Yimin Zhao, Yizhen Zhao, Shuyu Chen, Lu Gou, Xinghua Zhang, Shengli Zhang, Ming Li, Ximiao Hou*, Lei Zhang*, and Ying Lu*, Adv. Sci., 2024, 11(25): e2401150
10. Single-Molecule Monitoring of Membrane Association of the Necroptosis Executioner MLKL with Discernible Anchoring and Insertion Dynamics, Chenguang Yang#, Xiaolong He#, Hao Wang, Zhao Lin, Wenqing Hou, Ying Lu*, Shuxin Hu*, and Ming Li, Nano Letters, 2023, 23(11): 4770-4777
11. Correlative Escherichia coli Transcription Rate and Bubble Conformation Remodeled by NusA and NusG, Yuqiong Zhang, Weijing Han, Lisha Wang, Hao Wang, Qi Jia, Tongsheng Chen,* Shuang Wang,* and Ming Li, The Journal of Physical Chemistry B, 2023, 127(13): 2909-2917
12. Identification of flexible Pif1-DNA interactions and their impacts on enzymatic activities, Jinghua Li#, Jianbing Ma#, Vikash Kumar#, Hang Fu, Chunhua Xu, Shuang Wang, Qi Jia, Qinkai Fan, Xuguang Xi, MingLi, Haiguang Liu*, and Ying Lu*, Nucleic Acids Res., 2022, 50(12): 7002–7012
13. RQC helical hairpin in Bloom's syndrome helicase regulates DNA unwinding by dynamically intercepting nascent nucleotides, Jianbing Ma#, Chunhua Xu#, Jinghua Li, Xi-Miao Hou, Lin-Tai Da, Qi Jia, Xingyuan Huang, Jin Yu, Xuguang Xi*, Ying Lu*, and Ming Li, iScience, 2022, 25(1): 103606
14. Subnanometer-Precision Measurements of Transmembrane Motions of Biomolecules in Plasma Membranes Using Quenchers in Extracellular Environment, Wenqing Hou#, Dongfei Ma#, Xiaolong He#, Weijing Han, Jianbing Ma, Hao Wang, Chunhua Xu, Ruipei Xie, Qihui Fan, Fangfu Ye, Shuxin Hu, Ming Li*, and Ying Lu*, Nano Lett., 2021, 21(1): 485-491
15. Mismatch sensing by nucleofilament deciphers mechanism of RecA-mediated homologous recombination, Xing-Yuan Huang#; Ying Lu#; Shuang Wang#; Ming-Yu Sui; Jing-Hua Li; Jianbing Ma; Dong-Fei Ma; Qi Jia; Shuxin Hu; Chun-Hua Xu*; Ming Li*; Proceedings of the National Academy of Sciences of the United States of America, 2020, 117(34): 20549-20554
16. Dynamic structural insights into the molecular mechanism of DNA unwinding by the bacteriophage T7 helicase, Jian-Bing Ma#, Ze Chen#, Chun-Hua Xu#, Xing-Yuan Huang, Qi Jia, Zhen-Yu Zou, Chen-Yang Mi, Dong-Fei Ma, Ying Lu*, Hui-Dong Zhang*, and Ming Li*, Nucleic Acids Res., 2020, 48(6): 3156-3164
17. Mechanism of DNA translocation underlying chromatin remodelling by Snf2, Li, M#. Xia, X#. Tian, Y#. Jia, Q#. Liu, X#. Lu, Y. Li, M*. Li, X*. Chen, Z*., Nature, 2019, 567(7748): 409-413.
18. Detecting Single-Molecule Dynamics on Lipid Membranes with Quenchers-in-a-Liposome FRET, Ma, D. F. Xu, C. H. Hou, W. Q. Zhao, C. Y. Ma, J. B. Huang, X. Y. Jia, Q. Ma, L. Diao, J. Liu, C*. Li, M*. Lu, Y*., Angew Chem Int Ed Engl, 2019, 58(17): 5577-5581
19. Detection of tBid Oligomerization and Membrane Permeabilization by Graphene-Based Single-Molecule Surface-Induced Fluorescence Attenuation, Li Ma#, Shuxin Hu#, Xiaolong He#, Na Yang, Licui Chen, Chenguang Yang, Fangfu Ye, Taotao Wei*, and Ming Li*, Nano Lett., 2019, 19(10): 6937-6944
20. Watching Three-Dimensional Movements of Single Membrane Proteins in Lipid Bilayers, Ma Li; Li Ying; Ma Jianbing; Hu Shuxin*; Li Ming*, Biochemistry, 2018, 57(31): 4735-4740.
21. Asynchrony of Base-Pair Breaking and Nucleotide Releasing of Helicases in DNA Unwinding, Ma Jian-Bing; Jia Qi; Xu Chun-Hua; Li Jing-Hua; Huang Xing-Yuan; Ma Dong-Fei; Li Ming; Xi Xu-Guang*; Lu Ying*, Journal of Physical Chemistry B, 2018, 122(22): 5790-5796.
22. Functions of FACT in Breaking the Nucleosome and Maintaining Its Integrity at the Single-Nucleosome Level, Chen, P#. Dong, L. P#. Hu, M. L. Wang, Y. Z. Xiao, X. Zhao, Z. L. Yan, J. Wang, P. Y. Reinberg, D. Li, M. Li*, W. Li*, G. H*., Molecular Cell, 2018, 71(2):284-293
23. Helicase Stepping Investigated with One-Nucleotide Resolution Fluorescence Resonance Energy Transfer, Lin Wenxia#; Ma Jianbing#; Nong Daguan; Xu Chunhua; Zhang Bo; Li Jinghua; Jia Qi; Dou Shuoxing; Ye Fangfu; Xi Xuguang; Lu Ying*; Li Ming*, Physical Review Letters, 2017, 119(13): 138102
24. Free-Standing Single-Molecule Thick Crystals Consisting of Linear Long-Chain Polymers, Liu, Renwei#; Fan, Suna#; Xiao, Dongdong; Zhang, Jin; Liao, Mengzhou; Yu, Shansheng; Meng, Fanling; Liu, Baoli; Gu, Lin; Meng, Sheng; Zhang, Guangyu; Zheng, Weitao; Hu, Shuxin*; Li, Ming*, NANO LETTERS, 2017, 17(3): 1655-1659.
25. Single-molecule visualization of dynamic transitions of pore-forming peptides among multiple transmembrane positions, Li, Ying#; Qian, Zhenyu#; Ma, Li#; Hu, Shuxin; Nong, Daguan; Xu, Chunhua; Ye, Fangfu; Lu, Ying*; Wei, Guanghong*; Li, Ming*, Nature Communications, 2016, 7: 12906.
26. Pif1 is a force-regulated helicase, Li, Jing-Hua#; Lin, Wen-Xia#; Zhang, Bo; Nong, Da-Guan; Ju, Hai-Peng; Ma, Jian-Bing; Xu, Chun-Hua; Ye, Fang-Fu; Xi, Xu Guang; Li, Ming; Lu, Ying*; Dou, Shuo-Xing*, Nucleic Acids Research, 2016, 44(9): 4330-4339.
27. FACT Remodels the Tetranucleosomal Unit of Chromatin Fibers for Gene Transcription, Wei Li; Ping Chen; Juan Yu; Liping Dong; Dan Liang; Jianxun Feng; Jie Yan; Peng-Ye Wang; Qing Li; Zhiguo Zhang; Ming Li*; Guohong Li*, Molecular Cell, 2016, 64(1): 120-133.
28. Unwinding forward and sliding back: an intermittent unwinding mode of the BLM helicase, Shuang Wang, Wei Qin, Jing-Hua Li, Ying Lu, Ke-Yu Lu, Da-Guan Nong, Shuo-Xing Dou, Chun-Hua Xu*, Xu-Guang Xi,* and Ming Li, Nucleic Acids Res, 2015, 43(7): 3736-46